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  • Papain Powder 1
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  • Papain Powder 1
  • Papain Powder 2
  • Papain Powder 3

Papain Powder

High Activity Papain Powder of 200,000–2,400,000 U/g for Your Food, Pharma and Cosmetic Products

  • CAS Number: 9001-73-4
  • Molecular Weight: 21000Da
  • Chemical Name: Papain (or Papainase)
  • Related Name: Papaya peptidase I, Vegetable pepsin, Papain juice dry powder
  • Appearance: Light yellow powder

What Is Papain Powder?

Papain is a natural cysteine protease that is extracted from the latex of unripe papaya fruit. As a protein-cleaving enzyme, it can easily break down proteins. It is widely applied in multiple industries, including the pharmaceutical industry, the food industry, and the cosmetic industry.

Functions of Our Papain Powder

Baking Improvement and Cookie Shaping

Papain enzymatically hydrolyzes the gluten proteins in the dough. In this way, it reduces the strength of wet gluten and increases the extensibility of dough. This process improves the dough’s pliability and makes it easier to mold and shape. 

During baking, free amino acids generated in this process also react with reducing sugars and facilitate the Maillard reaction. This brings a uniform surface coloration. 

You can apply papain powder to your cookie production to avoid shrinkage or cracking. Your baking products will have well-defined patterns and consistent physical properties. 

Baking Improvement and Cookie Shaping
Efficient Animal and Plant Protein Hydrolysis

Papain exhibits high catalytic activity on various animal and plant proteins. Under moderate temperature and pH conditions, it converts large-molecular-weight proteins into low-molecular-weight peptides and free amino acids. The deep hydrolysis improves the water solubility and yield of the targeted protein. In this way, it liberates natural taste precursors.

You can utilize papain powder to optimize the production process of yeast extracts, hydrolyzed animal proteins, or plant-based proteins. Sunjoy offers high-activity papain powders of 800,000 to 1,000,000 U/g. It can optimize the enzymatic conversion, increase the raw material extraction yields, and reduce the total production cost.

Efficient Animal and Plant Protein Hydrolysis
Natural Meat Tenderization

Papain powder tenderizes meat without reducing its water-holding capacity by degrading the key protein. This reaction efficiently functions at room temperature and mild processing temperatures. 

If you need to improve the texture of meat, we recommend our papain powder with 100,000 to 200,000 U/g enzyme activity. It can make your meat products juicy and maintain the major nutrients.

Natural Meat Tenderization
Beverage and Beer Clarification

During the cooling process, some proteins easily combine with polyphenols and cause the beer or beverage to haze. Papain selectively breaks down these proteins into smaller, inactive fragments that are highly soluble. In this way, it prevents chill haze without interfering with or damaging foam-active proteins, and maintains the beer foam stable.

We suggest using this enzymatic solution to extend your products’ shelf life and improve their stability. With Sunjoy papain powder, your beer and beverages will maintain a clear appearance under cold storage conditions. The flavour and foam will not be influenced.

Beverage and Beer Clarification
Dietary Supplements

Papain remains active across a broad pH range (pH 4.5–8.5). It complements endogenous pancreatic proteases to break down dietary proteins. Papain assists in breaking down dietary proteins in the upper gastrointestinal tract when taken with meals and food nutrients. It also participates in degrading inflammatory mediators.

Sunjoy offers pharmaceutical-grade papain powder with activity up to 2,400,000 U/g. You can apply it to your digestive system supplements or multi-enzyme tablets. These products can help with absorbing proteins and reducing bloating.

Dietary Supplements D
Skin Brightening and Exfoliation

Papain breaks down the protein that binds dead cells together to help the old outer layer naturally shed off and accelerates the growth of new skin cells. By gently clearing dull surface buildup, it reveals a smoother, brighter complexion and helps even out skin tone.

You can use our cosmetic-grade papain powder in your premium skincare products as a mild solution to provide an alternative enzymatic exfoliation approach. It is ideal for facial cleansers, peeling masks, and brightening creams.

Skin Brightening and Exfoliation
Stain Removal

Papain can hydrolyze complex protein stains, such as blood, sweat, dairy, and food grease, into soluble peptide units. Then the stains can be easily cleaned with the surfactant molecules.

You can apply our papain powder to upgrade your detergent production line. It enables your detergents to remove tough organic stains at room temperature easily.

Stain Removal A
Feed Nutrition and Absorption

Papain powder can help with the problem of a lack of digestive enzymes. This issue commonly happens to young, early-weaned, or stressed animals. Papain breaks down the proteins in feed into digestible free amino acids and small peptides. This process reduces chyme viscosity in the intestine and increases feed conversion efficiency. 

You can use papain powder in your feed formulas to significantly optimize protein utilization and improve the daily weight gain of your livestock.

Feed Nutrition and Absorption
Baking Improvement and Cookie Shaping Efficient Animal and Plant Protein Hydrolysis Natural Meat Tenderization Beverage and Beer Clarification Dietary Supplements D Skin Brightening and Exfoliation Stain Removal A Feed Nutrition and Absorption

More About Our Company

  • Fully experienced in manufacturing papain powder since 2017
  • Has served brands across 50+ countries in the food, pharma, and cosmetic industries
  • Strict quality control to meet global market regulatory requirements (USP, FCC)
  • 10-20g Free sample reduces your procurement risk
  • Our stable supply chain ensures on-time delivery for your large volume orders

Maximized Enzyme Activity: Superior enzyme activity customizable from 200,000-2,400,000 U/g via advanced ultrafiltration and vacuum freeze drying. Pure enzymatic matrix for rapid protein cleavage and less formulation dosage.

High Production Standard: Manufactured in our GMP-certified factory. Strict biosecurity inspections ensure heavy metal, pesticide, and pathogen limits are controlled well below regulatory limits.

Cost Efficiency: Exceptional activity ensures maximum yield with minimum formula dosage. High activity also significantly reduces the reaction cycles and cuts the overall operational costs.

Excellent Stability: Resilient under a wide range of pH conditions. Formulated with glucose stabilization to prevent loss of enzyme activity. Guarantees consistency across batches.

Step 1: Papaya Latex Extraction and Dilution: We dilute fresh papaya latex with water diluted under controlled conditions to extract the active papain. This process reduces the viscosity and prepares for efficient filtration.

Step 2: Primary Centrifugal Clarification: The mixture is centrifuged to filter out large dregs. We discard the dregs and let the supernatant fluid undergo natural clarification. The fluid is separated into different density layers.

Step 3: Secondary Tube Centrifugation: The clarified supernatant is processed via a high-speed tube centrifuge to get a highly clear liquid. Meanwhile, the sediment is diluted with water and undergoes step 2 and step 3 once more to recover all active clear liquid.

Step 4: Microfiltration and Ultrafiltration: The combined clear liquids undergo microfiltration and ultrafiltration processes. In this step, micro residue is removed, and we concentrate the papain enzyme without damaging its bioactivity.

Step 5: Vacuum Freeze Drying and Pulverization: The concentrated liquid undergoes advanced vacuum freeze-drying to prevent the enzyme structure from denaturing when exposed to heat. Then, we crush and blend the dried cake into papain powder.

Step 6: Standardization with Glucose: We blend the semi-manufactured papain powder with food-grade glucose in a certain ratio. This process standardises enzyme activity to a specific customizer requirement and ensures consistency across batches.

Step 7: Quality Control and Subpackaging: Every batch of products undergoes strict QC testing. After verification, we pack the papain powder into protective containers to keep it from light and moisture.

Papain Production Parameter Specifications
Production StepKey Quality StandardEquipment UsedTesting and Monitoring
Step 1Water dilution ratio: 1:4Agitated Extraction TankFeedstock identity and temperature
Step 2Raw solids separationIndustrial CentrifugeClarity index and solid waste analysis
Step 3Reduced insoluble residuesTube CentrifugeLiquid flow rate and recovery rate
Step 4Retention of bioactivityMicropore / UltrafilterPore size integrity, and concentration ratio
Step 5Moisture content < 5.0%Vacuum Freeze DryerLoss on drying (LOD) and temperature
Step 6Activity conformity (U/g)Industrial BlenderPotency assay and homogeneity
Step 7Sealed and GMP compliantAutomatic Packaging LineMicrobial test; Heavy metals and Batch tracking
Papain Powder COA
Test ItemsSpecification Standards
AppearanceLight yellow color
OdorLight papain smell
Activity (U/g)≥600000
Moisture(%)≤8
Mesh(%)90% pass 80 mesh
Pb (mg/kg)≤3.0
As (mg/kg)≤3.0
Cd (mg/kg)≤1.0
Hg (mg/kg)≤0.1
Total plate count (CFU/g)≤10000
Coli group (CFU/g)≤30
Salmonella (25g)Absent
E.coli (CFU/g)Absent
Molds & Yeasts (CFU/g)≤100
MOQs25 kg/ drum
SampleAvailable (10-20 g/ bag)

Related Products

  • Bromelain Powder A

    Papain powder helps digest large protein molecules and improves nutrient absorption. In addition to digestive support, bromelain powder helps relieve muscle soreness caused by exercise. 

    You can apply them to your premium digestive health and sports recovery formulations. They are ideal for products such as multi-enzyme complexes, gut health supplements, and sports nutrition food.

  • β-Galactosidase A

    Papain powder can efficiently hydrolyze dietary proteins to relieve stomach burden and prevent bloating. β-Galactosidase targets lactose and reduces discomfort in the digestive system caused by lactose intolerance.

    You can combine them in your digestive support formulas and aim at lactose-sensitive populations.

  • Lysozyme Powder A

    Papain powder can help reduce localized swelling and tissue congestion by breaking down inflammatory proteins. Lysozyme powder can selectively target and hydrolyze bacterial cell walls. In this way, it maintains the microbial environment in balance and helps against inflammation.

    You can use these two ingredients in your advanced throat care formulations. They are optimal for various applications, including immunity-boosting supplements, throat lozenges, and natural food preservation systems.

  • Sodium Hyaluronate Powder A

    Papain powder removes dead surface cells gently through enzymatic action and makes the skin more easily absorb moisture. Sodium hyaluronate powder provides intense moisture for skin cells and locks the water in the skin.

    You can apply them to your skincare product line. They are suitable for products such as enzyme peeling powders, exfoliating cleansers, and mild skin-refining serums.

What Are the Side Effects of Papain Powder?

Dietary supplements and cosmetics that contain papain powder are commonly safe when used following the instructions. Most consumers tolerate papain well and rarely experience side effects. But when used improperly or in an overdose, it may increase the risk of side effects. 

For Supplements

  • Gastrointestinal and Localized Soreness (From Overuse)

Taking too many papain dietary supplements may cause temporary digestive discomfort, such as nausea, stomachache, bloating, and other discomfort in the digestive system.

  • Labelling Recommendation 

We recommend noting this information on your product label: Do not exceed the recommended daily dosage. If you have a digestive system disease, please consult a doctor before using.

For Skincare Products

  • Skin Irritation and Allergic Reactions 

Papain is an active exfoliating enzyme widely applied in leave-on or exfoliating skincare products. When the concentration or the frequency is too high, it may lead to temporary skin irritation, redness, stinging, or dryness.

Individuals who are sensitive to papaya or papain enzyme may experience allergic reactions, like itching, rash, or hives.

  • Labelling Recommendation 

We suggest advising your consumers to have a patch test before applying it for the first time. If irritation occurs, they should stop using it.

How Should I Store Papain Powder?

We suggest you store papain powder in a cool, dry place. It should avoid exposure to direct sunlight and moisture. Each time after dispensing it, seal the package to keep it from the air.

Under proper storage, the shelf life is over 24 months.

What Is the Assay Purity and IU Potency of Your Papain Powder?

Sunjoy offers food-grade and pharmaceutical-grade papain powder that meets the specifications of the United States Food Chemicals Codex (FCC) and the national specifications of China. Our papain powder has a wide activity range of 200,000 to 2,400,000 U/g. 

Papain Powder Grade Specification
Product GradeActivity RangeApplicable IndustriesCompliance Standards
Food Grade100,000 – 1,000,000 U/gMeat tenderizing, beer clarification, condiments, bakingFCC, GB, HALAL
Cosmetic Grade100,000 – 500,000 U/gEnzymatic exfoliation, skin brightening & whitening productsCosmetic ingredient regulations, non-irritation tested
Dietary Supplement Grade800,000 – 2,400,000 U/gDigestive enzyme capsules, multi-enzyme tabletsUSP, GMP

Whether you need papain powder capsules or tablet supplements, and whether you apply it in your food products or cosmetics, we can provide a customized solution for you. If you are confused about the selection of the activity, feel free to contact our service team for a tailored solution.

What Is the Solubility of Your Papain Powder?

Sunjoy papain powder is freely soluble in water. It dissolves quickly and forms a clear to slightly hazy solution. The excellent water solubility makes it ideal for both liquid formulations and dry powder blends.

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Looking for high-quality bulk papain powder? Sunjoy offers papain powder in various enzyme activities, manufactured to meet global industry standards. Contact us today and get your free sample and technical data sheet soon.

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