D-Alpha Tocopheryl Acetate
Pure D-Alpha Tocopheryl Acetate for Your Supplements and Cosmetic Products
- CAS Number: 58-95-7
- EINECS Number: 200-405-4
- Molecular Weight: 472.74
- Molecular Formula: C31H52O3
- Chemical Name: RRR-alpha-tocopheryl acetate
- INCI Name: TOCOPHERYL ACETATE
- Related Name: ATA, Natural Vitamin E Acetate, d-alpha-Tocopherol Acetate
- Appearance: slight light brownish to slight yellow oily liquid
What Is D-Alpha Tocopheryl Acetate?
D-Alpha Tocopheryl Acetate (ATA) oil is a clear liquid with a mild scent and taste. It is a stable, natural form of Vitamin E and is more stable compared to non-acetate forms of tocopherol. The major benefit is its powerful antioxidant activity. It is widely applied in oil-based supplements (such as softgels), nutritional food, and cosmetic products. For solid or water-dispersible formulations, please refer to our D-Alpha Tocopherol Powder.
Functions of Our D-Alpha Tocopheryl Acetate
ATA is an essential substance for maintaining the cardiovascular system’s health. It can inhibit excessive platelet aggregation and prevent low-density lipoprotein (LDL) from oxidation. In this way, ATA protects red blood cells and maintains the vascular endothelium smooth and elastic.
ATA oil is widely applied in products aimed at the senior population. It is also combined with other lipophilic nutrients like fish oil (Omega-3) and Coenzyme Q10 in complex supplements.
ATA is an efficient lipophilic antioxidant. It builds a defense for cells and blocks the lipid peroxidation chain reactions. ATA can also neutralize free radicals caused by UV light and environmental pollution. In this way, it protects cell walls from oxidative damage.
You can apply it in your daytime anti-photoaging serums, protective sunscreens, and anti-aging supplements.
ATA has exceptional biological repair and soothing activities. It helps reduce skin inflammatory responses caused by external irritants. ATA also helps with cellular microcirculation and the growth of fibroblasts. In this way, it helps support skin barrier maintenance and regeneration of damaged skin barrier and mucous membranes.
ATA is commonly used in products such as soothing creams after dermatological procedures, stretch mark prevention creams for pregnant women, and oral supplements for digestive system healthcare.
ATA is highly lipid-soluble and can blend into the lipid bilayer of the skin’s stratum corneum. It enhances the natural lipid barrier of the skin and significantly reduces transepithelial water loss (TEWL). It also moisturizes the deep layer of sensitive skin and dry skin.
ATA is widely applied in premium skin care products, such as anti-aging creams, deep-moisturizing lotions, repair creams for sensitive skin, and lip balms designed to prevent chapped lips.
More About Our Company
- Professional D-Alpha Tocopheryl Acetate Supplier
- Manufacturing
- Features
- Specification
- Our stable supply chain ensures on-time delivery for large volume orders
- Cooperate with international clients from over 50 countries
- 10 years of experience in producing D-Alpha Tocopheryl Acetate
- Compliant with global market requirements
Step 1: Non-GMO Soy Sourcing and Extraction: We extract high-purity d-α-tocopherol from premium, non-GMO soybeans. This ensures our source ingredient is 100% natural, compliant with the clean-label, and fully traceable.
Step 2: Precise Esterification for Stability: Sunjoy esterifies the natural d-α-tocopherol with high-quality acetic anhydride. In this step, we stabilize the active site and extend the shelf life of our products.
Step 3: Clarification and Decolorization: The mixture undergoes a strict filtration process. In this process, the trace residues and micro-particulates are eliminated, and we get a clear, transparent liquid base.
Step 4: Low-Temperature Solvent Removal: We use advanced low-temperature vacuum evaporation to remove all the reaction solvent. This process protects the fragile active molecules and ensures zero solvent residue.
Step 5: Advanced Molecular Distillation: We use advanced short-path molecular distillation to precisely isolate and concentrate the active Vitamin E. In this way, we extract pure D-Alpha Tocopheryl Acetate at its maximum potency of 1360 IU/g before standardization.
Step 6: Standardization and Ultrafiltration: We blend the purified oil base thoroughly to make sure every batch has a uniform color and potency. Then, it is processed with ultra-fine filtration for superior purity.
Step 7: Standardized Protective Packaging: Sunjoy has clean rooms that meet GMP standards. We seal the product into a pharmaceutical-grade and light-resistant container. It can keep our product from light and air to ensure stability in long-term storage.
| Quick Reference Sheet for ATA Production | |||
| Production Step | Key Quality Standard | Equipment Used | Testing and Monitoring |
| Step 1: Soy Extraction | Non-GMO, 100% traceable | Counter-current extraction line | Soybean feedstock identity testing (PCR for GMO detection, Acid Value, peroxide value) |
| Step 2: Esterification | Complete conversion | Glass-lined reactor | Acid value |
| Step 3: Clarification and Decolorization | Clear | Plate filter | Visual inspection |
| Step 4: Solvent Removal | Residue < 1ppm | Vacuum evaporator | Gas Chromatography (GC) |
| Step 5: Molecular Distillation | Assay: ≥1360 IU/g (Prior to standardization); eliminates heavy metals and impurities (Critical Control Point) | Short-path molecular distiller | HPLC potency testing and Heavy metals screen |
| Step 6: Standardization and Ultrafiltration | Guaranteed batch-to-batch consistency in color and potency | Blender and Ultra-filter | Particle size and Color scale |
| Step 7: Protective Packaging | Light-resistant and airtight | Automatic filling line | Seal integrity and Batch No. tracking |
High Stability: Excellent stability compared to d-alpha-tocopherol (AT). Optimized shelf life with enhanced heat and UV resistance reduces the return rate. It also protects other easily oxidized active ingredients from premature degradation.
100% Natural Source: Derived from non-GMO soy oil. Natural source brings two times the biological retention of synthetic VE. Highly absorbable for the human body.
Excellent Compatibility: High biocompatibility with the skin minimizes irritation. Excellent oil solubility makes it easily applied to cosmetics and supplements.
Release Targetedly: Protects the formula on the skin or activates after taking as an oral supplement. Zero potency cost in the bottle. Maintains inactivity during storage and transportation.
| D-Alpha Tocopheryl Acetate COA | ||
| Items tested | Specifications | |
| Assay | ≥73.5 % ≥1000 IU | |
| Identification 1) Color reaction 2) Specific Rotation [α]D25℃ 3) Retention Time | Positive | |
| ≥+24° | ||
| The retention time of the major peak in the test solution is the same as that of the standard preparation. | ||
| Acidity | ≤1.0 ml | |
| Benzo(a) Pyrene | ≤2 ppb | |
| Solvent residue-Hexane | ≤290 ppm | |
| Heavy Metals (As Pb) ≤10 mg/kg | Lead | ≤ 1 mg/kg |
| Arsenic | ≤ 1 mg/kg | |
| Cadmium | ≤ 1 mg/kg | |
| Mercury | ≤ 0.1 mg/kg | |
| Total Bacterial Count | ≤ 1000 cfu/g | |
| Yeast and Molds | ≤ 100 cfu/g | |
| Escherichia Coli | ≤ 10 cfu/g | |
| Salmonella | Negative / 25g | |
| Staphylococcus Aureus | Negative / 10g | |
| MOQs | 25 kg/ drum | |
| Sample | Available (10-20 g/ bag) | |
Related Products
Vitamin E and Vitamin C are a golden antioxidant duo. 3-O-Ethyl Ascorbic Acid is a highly stable Vitamin C derivative. D-Alpha Tocopheryl Acetate removes lipid peroxides on the cell walls. 3-O-Ethyl Ascorbic Acid regenerates the oxidized VE back to the active form. This recycling mechanism expands the antioxidant cycle of your products significantly.
You can apply them in your cosmetic products, such as premium anti-aging serums, and market them with long-term antioxidant function.
D-Alpha Tocopheryl Acetate acts as the barrier on the lipid layer. L-Glutathione Reduced removes reactive oxygen species (ROS) in the cells. They build a protective system both inside and outside the cells. L-Glutathione Reduced also helps maintain ATA in the reduced state.
You can combine them in your premium cellular protection and hyperpigmentation control formulations. They are suitable for oral beauty supplements, brightening skincare formulations, and liver detox supplements.
Coenzyme Q10 and ATA are both lipid-soluble antioxidants. Co Q10 optimizes the generation of ATP, while ATA protects the outer membrane structures. They coordinate to help reduce UV-induced photoaging and cardiovascular oxidative stress.
We recommend you make them a combo for your vascular support supplements and aim at the premium market.
ATA can repair the lipid barrier and lock moisture from transepidermal water loss (TEWL). Sodium hyaluronate combines with moisture deeply in the extracellular matrix. For dry, compromised, and mature skin, this combo provides a shield and an infiltration solution.
You can apply them to your hydrating anti-wrinkle creams, post-procedure healing topicals, and functional beverages.
The main differences are the chemical stability and applications. In general, D-Alpha Tocopheryl Acetate is more stable than D-Alpha Tocopherol. Here is a table for quick reference.
| D-Alpha Tocopheryl Acetate (ATA) vs D-Alpha Tocopherol (AT) | |||
| Product Form | Primary Application | Key Strength | Antioxidant Action |
| ATA | Dietary supplements, softgels, tablets, and fortified foods | High stability against light, heat, and air; long product shelf-life | Activated inside the human body after consumption |
| AT | Cosmetics, topical skincare creams, and lipid-based food preservation | Immediate antioxidant protection within the formulation | Acts directly within the product formula to prevent rancidity |
D-Alpha Tocopheryl Acetate (ATA)
ATA is the esterified form of Vitamin E. The ester bond protects the active site and makes it highly resistant to light, heat, and oxidants induced by air. In this way, the shelf life of your final products is significantly extended.
ATA does not play the role of an antioxidant in the bottle. But once it is taken into the human body, the enzymes in the digestive system convert it into active D-Alpha Tocopherol (AT), and deliver high bioavailability.
If you are developing and producing products that require a long shelf life and are easy to store, ATA is your ideal choice.
D-Alpha Tocopherol (AT)
AT is the free, unesterified form of natural Vitamin E. It functions as a powerful antioxidant when it is in the bottle. It can prevent oil-based ingredients from going rancid. AT is very sensitive to light, heat, and ambient air. It requires strict oxygen-free storage and careful handling. It is not suitable for daily supplements.
D-Alpha Tocopheryl Acetate is known as a highly safe nutrient supplement ingredient. As a natural and stable form of Vitamin E, most people are well-tolerated to it. It rarely causes side effects when it is used at the recommended daily dosage. In specific cases (especially in overdosed and allergic cases), it may cause the following side effects:
Digestive and General Discomfort (From Overuse)
If your consumers take excessive amounts of ATA supplements, side effects including nausea, stomachache, diarrhea, fatigue, weakness, dizziness, headaches, or blurred vision may occur.
We suggest printing this advice on your product label: If you have already taken multivitamin formulas that contain Vitamin E, avoid taking additional Vitamin E supplements.
Mild Allergic Reactions (Rare)
Allergic reactions to ATA supplements are quite uncommon. But some individuals may experience localized skin redness, itching, rashes, or hives after taking ATA products.
Interactions with Anticoagulant Medicines
Taking high doses of ATA may interfere with blood clotting and increase the risk of bleeding. A clear warning should be included on the product label regarding concurrent use with blood thinners or anticoagulant medications (such as warfarin or aspirin).
We highly recommend noting this information on your product label.
We recommend storing the ATA oil in sealed containers and strictly avoiding light and oxygen. Keep it from alkali and oxidizing agents. In normal storage conditions, the shelf life is over 24 months.
Sunjoy produces D-Alpha Tocopheryl Acetate with non-GMO soy as feedstock. You can apply it in your high-end product line and highlight non-GMO in the promotion.
Our ATA oil meets the global standard of 1000 IU/g. Its assay purity is over 73.50% (equivalent to 1000 IU/g). The remaining 26.50% consists of premium USP-grade Medium Chain Triglycerides (MCT oil) as a carrier, standardized to ensure consistent viscosity, easy pumpability, and precise dosage control.
It is used for consistent dosage in every batch and optimized viscosity. When you are manufacturing soft gels and skincare creams, the carrier oil reduces the risk of clogging.
Contact Us
If you are looking for D-Alpha Tocopheryl Acetate oil for your supplements or cosmetic products, Sunjoy offers you ATA oil of high bioactivity and stability. Contact us today and get your ATA oil soon.
