Bulk L-Arginine Alpha-Ketoglutarate Powder Manufacturer in China
Sunjoy provides quality-assured L-arginine alpha-ketoglutarate for your formulas.
- CAS number: 5256-76-8; molecular formula: C17H38N8O11; molecular weight: 530.5
- Related name: L-Arginine AKG, Arginine Alpha-Ketoglutarate, AAKG
- Grade available: Food Grade / Cosmetic Grade / USP Pharmaceutical Grade
- Solubility: soluble in water
- Appearance: white or off-white, crystal or powder
- Packaging: 1 kg aluminum foil bags, 25 kg fiber drums with inner double-layer PE bags
What Is L-Arginine Alpha-Ketoglutarate (AAKG)?
L-arginine alpha-ketoglutarate (AAKG) is a compound salt ingredient formed by L-arginine and alpha-ketoglutarate. It is also called L-arginine AKG and arginine alpha-ketoglutarate. Compared with L-arginine, AAKG is more ideal for blended functional products.
Due to AAKG’s involvement in metabolism, it is now widely used as an AAKG supplement raw material in pre-workout supplements, amino acid blends, muscle nutrition formulas, and dietary supplements.
Applications of Sunjoy L-Arginine Alpha-Ketoglutarate
L-arginine can provide arginine, and the alpha-ketoglutarate can participate in cellular energy metabolism. Thus, AAKG is widely used in sports nutrition products and bodybuilding formulas. With the growing demand in Europe, the United States, and Southeast Asia, AAKG is widely selected by supplement manufacturers for commercial formulations.
As an amino acid ingredient, AAKG can be used in functional foods and nutritional supplements. The advanced water solubility and processing compatibility enable its application in functional beverages, powders, and other dosage forms.
AAKG can serve as an amino acid-derived ingredient in medical nutrition products. For formulation development, AAKG is also studied for its potential applications in vascular function support, protein metabolism regulation, immune support, and tissue repair.
As a natural amino acid, L-arginine is commonly used in amino acid supplements and skin care products. AAKG can be used in some formulations, such as moisturizers and skin-conditioning products. Besides, AAKG’s potential in blood circulation support also enables its application in some scalp and hair care products.
More About Our Company
- Professional L-Arginine Alpha-Ketoglutarate Manufacturer
- Features
- Manufacturing Processes
- Certificate of Analysis
- Transparent, traceable AAKG industrial lines
- Manufacturing lines comply with GMP and ISO requirements
- USP/BP grade AAKG raw material available upon request
- Customizable food, cosmetic, and pharmaceutical-grade ingredients
High Purity L-Arginine Alpha-Ketoglutarate: After multiple rounds of purification, we ensure our AAKG meets purity standards and is compatible with supplements and sports nutrition.
Consistent AAKG Content: Through standardized manufacturing procedures and strict specification control, every batch maintains the same content.
Traceable Management: We establish a comprehensive traceability system. From raw material sourcing and manufacturing to final testing, we ensure our AAKG is traceable and quality-assured.
Superior Processing Compatibility: Our AAKG can quickly dissolve in water. With advanced stability and particle size control, our ingredients exhibit superior powder flowability, suitable for different dosage forms.
Comprehensive Inspection: All our AAKG needs to undergo comprehensive tests, with specifications including assay, moisture, heavy metals, and other parameters.
Documentation Support: For global logistics and regulatory requirements in different markets, we provide documentation. Optional certifications include halal, kosher, and non-GMO certificates.
Reliable Bulk Supply: We have mature manufacturing lines compliant with GMP and ISO, and reliable raw material supplies. Thus, we can continuously produce AAKG for your bulk orders.
Flexible MOQ: Starting at 1 kg, we offer flexible MOQ for your program from formulation development to final commercial manufacturing.
Raw Material Preparation and Testing: Before manufacturing, we prepare L-arginine, alpha-ketoglutaric acid, and other raw materials. Quality inspections are conducted, including parameters like assay, moisture, heavy metals, and microbials. We ensure that our raw materials meet the manufacturing standards.
Ingredient Mixing: According to the target molar ratio 2:1, we accurately weigh L-arginine and alpha-ketoglutaric acid. We use high-shear mixing technology to ensure uniform powder dispersion and precise ratio. In this stage, these two materials form the stable compound salt of L-arginine alpha-ketoglutarate (AAKG).
Cooling Process: We use controlled cooling technology to control the crystallization process. In this procedure, the salt is more stabilized at a reduced, even temperature. Through this standardized cooling process, we improve the AAKG quality consistency.
Grinding and Milling: Cooled AAKG goes into mills to produce fine powder. Common machines include hammer mills, pin mills, and air classifying mills. In grinding and milling, we reduce the particle size and improve the AAKG powder flowability.
Drying: This is a critical control point that needs closed monitoring. At this stage, temperature and moisture are controlled. We use vacuum drying technology to evaporate moisture at a lower temperature, reducing the heat influence on AAKG.
Powder Separation and Particle Size Control: Vibrating sieving and air classification are common technologies used to control the particle size. Oversized AAKG particles are removed, ensuring uniform, even powder flowability. The controlled particle size is suitable for various dosage forms of products and reduces moisture absorption concerns, which is important due to the highly hygroscopic nature of AAKG.
Quality Testing and Packaging: We have a comprehensive quality testing system. Common tested specifications include HPLC assay, moisture, heavy metals, microbials, and other parameters. Multiple tests ensure that your AAKG meets the regulatory standards of your target markets. You don’t have to worry about your product quality.
Our standardized packaging is 1 kg aluminum foil bags and 25 kg fiber drums with inner double-layer PE bags. This packaging keeps AAKG away from heat, light, and moisture, reducing the risks of caking or degradation.
| Item | Specification |
| Appearance | White or off-white, crystal or powder |
| Specific Rotation | +16.5° ~ +18.5° |
| Solubility | Readily soluble in water, and the solution is clear |
| Assay | 98.0%-102.0% |
| L-arginine Content | 65.5%-69.0% |
| Alpha-ketoglutarate Content | 26.5%-29% |
| Water Determination | ≤7.8% |
| Loss on drying | ≤1.0% |
| Storage | Store in cool, dry, and well-ventilated places, away from moisture, heat, and direct sunlight. The product is highly hygroscopic. Please seal tightly after use to avoid moisture absorption from the air. |
| Shelf Life | 24 months if appropriately stored. |
| MOQ | Flexible MOQ starting at 1 kg |
| Samples | 10 g-20 g free samples available, and shipping costs will be covered by the clients |
| Dispatch Time | Within 5-7 business days after payment |
Related Products
Used in sports nutrition, protein supplements, and amino acid blends.
Used in sports nutrition, muscle nutrition products, and functional nutrition.
Used in dietary supplements, sports nutrition, and mineral nutrition products.
Used in dietary supplements, beauty nutrition, and antioxidant formulations.
| Parameters | L-Arginine Alpha-Ketoglutarate (AAKG) | L-Arginine | L-Citrulline |
| Relationship | L-arginine + alpha-ketoglutarate, a stable salt form | L-citrulline can be converted into L-arginine | L-arginine can be converted into L-citrulline |
| Suitable Positioning | Suitable for comprehensive sports nutrition and amino acid blends | Basic arginine supplement ingredients | Citrulline-based sports nutrition ingredient |
| Primary Application | Pre-workout products, sports nutrition powders, amino acid blends, and functional nutrition formulas | Dietary supplements, amino acid products, sports nutrition products, and fortified formulas | Premium pre-workout products, sports nutrition supplements, and amino acid blends |
| Common Ingredient Combination | Sports nutritional ingredients such as BCAAs, protein powder, creatine, vitamins, and minerals | Other amino acids and protein nutrients | Other sports nutrition amino acids |
| Costs | Medium | Lower | Higher |
These three ingredients can all provide amino acid supplements for your products. However, when choosing formulation ingredients, you can consider your product positioning, target market, formulation requirements, and your budget.
If you plan to develop sports nutrition, pre-workout supplements, or compound amino acid formulations, AAKG is recommended. It features superior processing compatibility. Besides, it is in a stable salt form, ideal for long-term storage and commercial manufacturing.
If you need a single amino acid source for basic nutritional support, L-arginine is suitable. This ingredient also features a more budget-friendly price, ideal for your large-scale manufacturing.
If you are designing premium sports formulations, L-citrulline is a good choice. Although it has a higher price, it has gained recognition in the high-end markets.
Energy Support
What does AAKG do? You may have this question. AAKG is involved in amino acid and protein metabolism and cellular energy generation. It offers energy support for metabolism. Thus, AAKG is a nutritional ingredient used in functional foods and energy beverages.
Nitric Oxide Synthesis
L-arginine is an important substrate for the synthesis of nitric oxide (NO). Catalyzed by nitric oxide synthase, L-arginine in AAKG is converted into L-citrulline and NO. So, AAKG is commonly studied for its NO synthesis support.
Muscle Nutrition Support
AAKG is involved in protein synthesis, laying the foundation for muscle maintenance and growth. The alpha-ketoglutarate is an important intermediate metabolite. It participates in energy generation and provides metabolic support for cells. Thus, our AAKG can provide nutritional support for muscles and sports activities.
Clinical and Tissue Recovery Research
Tissue recovery requires new structural proteins, and AAKG participates in protein synthesis and metabolism. AAKG is also helpful for nitric oxide synthesis, which is important for vascular circulation and tissue nutrition. Thus, AAKG is studied for tissue maintenance.
Vascular Function Support
AAKG provides L-arginine for nitric oxide synthesis, which participates in vascular maintenance and function. Therefore, AAKG is studied and used for its potential in vascular management.
Commonly, AAKG is well tolerated when used at the recommended dosage. However, there are still some mild side effects. These reactions listed are for reference only. For more detailed and professional suggestions, please consult doctors.
Mild Digestive Reactions
When taking AAKG in excess or supplements containing too much AAKG, people may experience some mild gastrointestinal reactions, such as abdominal bloating, nausea, abdominal discomfort, and changes in bowel habits. When developing formulations, it is recommended to carefully design the AAKG dosage.
Allergic Reactions
Some people may be allergic to AAKG, L-arginine, or alpha-ketoglutarate. When taking AAKG, they may experience side effects such as itchy skin, rash, swollen face or mouth, difficulty breathing, and other reactions. When side effects occur, people should discontinue use immediately and seek medical attention.
For bulk orders and mass production, assured quality and stable batch consistency are important. Thus, we can ensure reliable ingredient performance in your formulations. Through a controlled manufacturing process, quality testing, and documentation support, we offer high-assay AAKG with consistent quality.
Controlled Manufacturing Process
To ensure stable AAKG quality, first, we establish standardized manufacturing lines compliant with ISO and GMP. The consistent production process ensures that every batch of AAKG experiences the same manufacturing process and has the same properties.
Comprehensive Quality Control
We also have a full set of tests. In raw material preparation, manufacturing process, and final product evaluation, we monitor and test material specifications and production conditions to ensure AAKG meets quality standards. Actually, only qualified AAKG batches can be shipped. So the products you receive are all quality guaranteed.
Quality Documentation
We not only ensure AAKG quality, but also provide quality documents for our products. We provide COAs, third-party inspections, and other traceable documents in manufacturing. With these papers, we can verify our product quality to customs and your target markets.
Contact Us
If you are sourcing bulk L-Arginine Alpha-Ketoglutarate powder, Sunjoy is your reliable ingredient supplier in China. From formulation design to commercial ingredient procurement, we provide you with the best AAKG. Contact us and send your inquiries!
