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  • Riboflavin Powder 1
  • Riboflavin Powder 2
  • Riboflavin Powder 3
  • Riboflavin Powder 1
  • Riboflavin Powder 2
  • Riboflavin Powder 3

Riboflavin Powder

Pure Riboflavin Powder For Your Health Care Brand 

  • CAS Number: 83-88-5
  • EINECS Number: 201-507-1
  • Molecular Weight: 376.36
  • Chemical Name: Riboflavin
  • Molecular Formula: C17H20N4O6
  • Related Name: Vitamin B2, Lactoflavin, Ovoflavin, Hepatoflavin
  • Appearance: Yellow or orange-yellow crystalline powder
  • Solubility: Slightly soluble in water; practically insoluble in ethanol, chloroform, and ether

What Is Riboflavin Powder?

Riboflavin is a water-soluble micronutrient. Its commercial name is Vitamin B2.  Riboflavin is a necessary substance for the human body and supports growth and cellular functions. It is the precursor for two major coenzymes, FMN and FAD. These coenzymes catalyze oxidation-reduction reactions and convert nutrients into cellular energy.

Riboflavin powder is widely applied in supplements, functional foods, and as a natural yellow colorant in pharmaceutical formulas.

Sunjoy Riboflavin Powder Applications

Promote Growth and Cellular Regeneration

Vitamin B2 (Riboflavin) is an essential precursor to flavin coenzymes (FAD and FMN). It widely participates in the metabolic processes of protein, fat, and carbohydrate. For growing children and teenagers, adequate Vitamin B2 intake helps the body in normal energy conversion and healthy growth.

As a key nutrient in cellular metabolism, Vitamin B2 supports the integrity of cell wall structure and biological functions. It plays a great role in natural tissue renewal and cellular repair and helps maintain overall physical well-being.

Promote Growth and Cellular Regeneration
Support Skin, Hair, and Nail Health

Vitamin B2 deeply participates in the metabolism and differentiation of epithelial cells. It helps maintain the moisture-oil balance of the skin surface and regulates normal skin cell turnover. In this way, it enhances the skin barrier and helps defend against UV light, air contamination, and other environmental stresses that can cause damage to the skin.

The growth of nails and hair highly depends on active cellular metabolism and nutrient synthesis. Vitamin B2 helps maintain the strength and natural shine of the nail and reduces brittleness. It also supports the cell metabolism of hair follicles. In this way, it helps the hair grow healthily.

Support Skin, Hair, and Nail Health
Support Mucosa and Oral Health

Vitamin B2 is essential for oral mucosa health. It can help deal with the discomfort caused by a lack of nutrition or dietary nutrient deficiencies. 

Vitamin B2 also helps maintain the physiological balance in the lips and oral mucosa. It accelerates the natural self-repair process of mucosal tissues and maintains lip and tongue moisture. In this way, it reduces chapped lips and discomfort, keeping the oral environment healthy.

Support Mucosa and Oral Health
Support Eye and Visual Health

Vitamin B2 helps maintain the normal metabolism of retinal and eye tissues. It helps the eyes adapt to variations in lighting conditions and supports healthy visual performance.

For people with prolonged screen time, taking adequate Vitamin B2 supplements can help relieve eye fatigue and maintain eye health.

Support Eye and Visual Health
Promote Growth and Cellular Regeneration Support Skin, Hair, and Nail Health Support Mucosa and Oral Health Support Eye and Visual Health

More About Our Company

  • Advanced equipment and stable supply chain for bulk orders
  • 10 years of experience in producing riboflavin powder
  • Partner with global brands across more than 50 countries
  • Compliant with overseas markets’ regulatory requirements
  • Free 10-20 g sample for lab testing

Superior Purity: Sunjoy strictly controls residue to ensure exceptional purity of over 98%. It has a high safety level and consistent bioactivity. Our powder meets the specifications of pharmaceutical, nutraceutical, and food-grade applications.

Competitive Price: As a direct manufacturer, Sunjoy provides competitive factory pricing and stable supply for bulk. For bulk orders over 100 kg, we provide direct factory tier pricing. 

Stability and Coloring: Our riboflavin powder has outstanding thermal resistance and low processing degradation. It provides a unified and continuous golden-yellow coloration and ensures visual consistency and reliable nutrient potency across various processes.

Excellent Flowability and Granulation: A unified particle size efficiently reduces dust, prevents caking, and offers exceptional flowability. These features make our product ideal for direct compression, tablet pressing, capsule filling, and high-speed automated blending.

Our Riboflavin powder is produced through a microbial fermentation process, which is eco-friendly and highly controlled. We produce Vitamin B2 powder through multiple processes and inspections to ensure high purity, stable crystal structure, and full compliance with USP/EP standard requirements.

The entire production has these 4 core stages: 

Step 1: Strain Activation and Culture Prep: The selected production strains are activated and cultivated in sterile shaker flasks. Then they are transferred to the seed pots with specific nutrition formulations for scaling up.

Step 2: Sterile Aerobic Fermentation: The active seed culture is transferred into the large-scale fermenters. We purify the compressed air to sterile air before it enters the fermenters. In this way, we ensure a strictly sterile, oxygen-rich environment for optimal microbial production.

Step 3: Filtration and Multi-Stage Crystallization: The fermented broth produced in the last stage is effectively filtered to separate the biomass and clear solution. The crude product undergoes primary crystallization. Then it is processed with targeted decolorization to remove the color impurities. It goes through a re-crystallization to reach the high molecular purity of Assay 98.0%–102.0%. 

Step 4: Centrifugation, Drying and Packaging: We use high-speed centrifuges to separate the crystals and the mother liquor efficiently. Then the crystals are dried in a double-cone rotary vacuum dryer for a low moisture content of ≤1.5%. This ensures a uniform heat distribution without light-induced degradation.

We pack the powder in a clean room (D-Grade/100,000 class). The powder is packed in light-proof, sealed packaging to prevent oxidation and light exposure.

Riboflavin Powder COA
Test ItemsUSP2024 StandardTest Method
DescriptionYellow or orange-yellow crystalline powderVisual
IdentificationIntense yellowish-green fluorescence that disappears upon the addition of mineral acids or alkalies.USP <197>
Lumiflavin≤0.025%USP <857>
Specific rotation−115∘∼−135∘USP <781S>
Assay98.0∼102.0%USP <853>
Loss on drying≤1.5%USP <731>
Residue on ignition≤0.3%USP <281>
Lead≤1ppmUSP <251>
Heavy metals(Pb)≤10ppmUSP <231>
Cadmium≤1ppmUSP <851> AAS
Mercury≤0.1ppmUSP <261>
Arsenic≤1ppmUSP <211>
Bulk density≥0.30g/mlUSP <616>
Particle Size95% passes through 80 meshUSP <786>
Aerobic Plate Count≤1000CFU/gUSP <2024>
Yeast and moulds≤100CFU/gUSP <2024>
E. coliNegativeUSP <2024>
Other
MOQs25 kg/ drum
SampleAvailable (10-20g/ bag)

Related Products

  • Pyridoxal-5'-Phosphate Powder (P5P) A
    Pyridoxal-5'-Phosphate Powder (P5P)

    P5P is an active form of Vitamin B6. It supports the generation of neurotransmitters and amino acid metabolism. While Riboflavin-derived coenzymes support enzymes involved in Vitamin B6 metabolism.

    You can combine them as a golden duo for your premium Vitamin B complex formulations. We suggest aiming at populations demanding superior bioavailability.

  • Thiamine Nitrate A

    Thiamine Nitrate provides the necessary Vitamin B1 to help convert cellular carbohydrate and promote the functions of the nervous system. Riboflavin coordinates with Thiamine Nitrate to produce ATP in the mitochondrial energy pathway.

    You can combine these two ingredients in your fatigue-relief products and aim at busy professionals and fitness enthusiasts.

  • Coenzyme Q10 Powder A

    Coenzyme Q10 drives the electron transport in the mitochondria. In this way, it supports generating ATP to protect cells from oxidant reactions. Vitamin B2 provides the essential flavin coenzymes (FAD/FMN) that are required for the maintenance of continuous mitochondrial respiration.

    You can use them in your cellular vitality and cardiovascular formulas and target senior populations.

  • Calcium L-5-Methyltetrahydrofolate A

    Calcium L-5-Methyltetrahydrofolate offers active folate to regulate homocysteine levels and promote cellular methylation. Vitamin B2 activates the MTHFR enzyme. This is necessary to maintain the efficient functioning of folate pathways.

    You can apply both of them in your products for cardiovascular and prenatal health.

How Should I Store Riboflavin Powder Properly? What Is Shelf Life?

Sunjoy Riboflavin powder is heat-resistant. But it is sensitive to light (especially UV light) and moisture. 

We recommend storing it under cool, dry, and well-ventilated conditions and avoiding direct sunlight and strong oxidizing agents. (Below 25°C and relative humidity below 60%)

We pack Vitamin B2 powder in a sealed food-grade PE bag within a sealed fiber drum. Each time after using it, please seal it at once. 

Under the proper storage conditions, the shelf life is over 24 months.

What Are the Recommended Usage Levels and Regulatory Standards for Riboflavin (Vitamin B2) in Different Food Products?

Riboflavin powder has two functions in the food industry. It is applied as both a colorant (color additive) and a nutrient fortifier. 

According to the regulatory requirements of different countries, such as GB 2760 / GB 14880 standards in China, the typical usage levels and primary functions are different. 

The table below is a quick reference for the dosage of different applications and functions. If you need more details, please contact our service team for specific information on your products and requirements.

Dosage Guidelines and Regulatory Limits for Riboflavin (Vitamin B2)
Additive NameFood Category ApplicationPrimary FunctionTypical Usage Levels and Regulatory ConsiderationsNotes and Additional Info
Vitamin B2Instant rice and noodle productsColorant0.05 g/kgProvides stable, bright yellow tone
Vitamin B2Western pastries and baked goodsNutrient Fortifier0.33 – 0.70 mg / 100gUsed for nutritional fortification in bakery
Vitamin B2Sports nutrition foodsNutrient Fortifier0.2 – 20 mg (per daily serving/portion)Helps energy metabolism for active individuals
Vitamin B2Solid compound seasoningsColorant0.05 g/kgDisperses evenly in dry powder mixes
Vitamin B2Follow-up formula for older infants and young childrenNutrient Fortifier0.4 – 2.0 mg / 100gStrictly regulated for early childhood nutrition
Vitamin B2Biscuits and cookiesNutrient Fortifier0.33 – 0.67 mg / 100gHeat-stable during baking processes
Can Riboflavin Powder Locally Applied Heal Denture Sore Spots?

No. Although Vitamin B2 powder is vital to the health of mucosal and tissue repair, it is still not recommended to apply it directly to the denture sore spots. This is because the pure powder has low bioavailability in local application, and the unbuffered particles can cause irritation.

If you are developing products for oral mucosal discomfort or denture sores, oral mucosal repair gels, protective ointments, and functional lozenges are ideal forms. 

Sunjoy provides riboflavin powder that meets USP/EP standards. Our Vitamin B2 powder has controlled particle size distribution and high purity. It can be evenly dispersed in a hydrogel or cream matrix and improve the texture and skin adherence of the final product.

What is the Degraded Color of Riboflavin Powder? How to Figure Out If It Is Degraded?

The degraded Riboflavin powder is brownish-orange or reddish, while pure riboflavin powder is yellow to orange-yellow. 

When pure Vitamin B2 powder is exposed to light or alkaline conditions in the long term, it will be degraded into lumiflavin or lumichrome. This causes the color change and the loss of its bioactivity as a Vitamin B2 precursor (FAD/FMN). Therefore, we highly recommend keeping the Riboflavin powder from light (especially UV light) exposure.

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If you are searching for riboflavin powder for your brand, Sunjoy offers you pure, stable, and cost-effective riboflavin powder. Contact us now and download the full COA, MSDS, and HPLC test reports.

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