S-Adenosyl-L-Methionine Disulfate Tosylate for Sale
Sunjoy provides reliable S-adenosyl-L-methionine disulfate tosylate for your formulations.
- CAS number: 97540-22-2; molecular formula: C22H34N6O16S4; molecular weight: 766.8; EINECS number: 249-946-8
- Related name: SAMe disulfate tosylate
- Freely soluble in water and slightly soluble in ethanol
- Appearance: white to off-white powder; packaging: 25 kg fiber drums with inner double-layer plastic bags
What Is S-Adenosyl-L-Methionine Disulfate Tosylate?
S-adenosyl-L-methionine (SAMe) is a bioactive molecule that occurs naturally in human bodies. S-adenosyl-L-methionine disulfate tosylate (SAMe disulfate tosylate) is one of the widely applied commercial forms of SAMe. Compared with the free SAMe base, SAMe disulfate tosylate is more stable and more ideal for storage and shipping.
What Is S-Adenosyl-L-Methionine Disulfate Tosylate Used For?
SAMe is a critical methyl donor for glutathione. As glutathione is vital in antioxidant and detoxification metabolism in the liver, Sunjoy SAMe disulfate tosylate is also used in dietary supplements and nutritional formulas designed to support liver health.
SAMe plays a part in the synthesis and metabolism of serotonin, dopamine, and norepinephrine. So, combined with B vitamins, folic acid, and magnesium, Sunjoy SAMe disulfate tosylate is widely used in emotional balance and mental health products.
SAMe engages in the metabolism of cartilage and connective tissue. Together with glucosamine, chondroitin sulfate, and MSM, Sunjoy SAMe disulfate tosylate is used in dietary supplements for joint nutrition.
Sunjoy SAMe disulfate tosylate can be combined with ingredients such as melatonin, magnesium, and L-theanine to develop sleep-health support products.
More About Our Company
- Professional S-Adenosyl-L-Methionine Disulfate Tosylate Supplier
- Features
- Synthesis
- Certificate of Analysis
- Export services for clients from 50+ countries and regions
- Strict quality control provides reliable, premium products
- 10+ years of experience in manufacturing SAMe
- Reliable, continuous supply for your formulas
98%+ Assay: High-assay SAMe disulfate tosylate meets your requirements for qualified raw materials, providing a reliable foundation for formula development.
Stable Form of SAMe: The entire salt-forming reaction is conducted in a low-temperature system. Improved chemical stability enhances storage, shipping, and manufacturing performance.
Good Water Solubility: SAMe disulfate tosylate freely dissolves in water, making it suitable for various dietary supplement formulations and processing requirements.
Batch Consistency: We have standardized manufacturing processes and strict quality controls. The entire monitoring process ensures our product remains consistent between batches.
Strict Impurity Control: We test for impurities, heavy metals, and other residues, ensuring our SAMe disulfate tosylate can successfully enter the US, EU, and other markets.
Market Compliance: We provide quality-assured powder compliant with ISO, GMP, and FSSC requirements, ensuring your cargo successfully enters your target markets.
Reliable Supply: We have well-established production lines and reliable supply chains, continuously providing premium SAMe disulfate tosylate.
Custom Service: We provide custom services, including options like packaging, particle size, and other parameters tailored to your requirements.
Microbial and Seed Culture: Sunjoy adopts a multi-stage seed culture process and strict control over culture conditions. With close monitoring of strain and seed activity, we ensure a stable fermentation process, providing a reliable basis for efficient SAMe synthesis.
Fermentation: We have a mature, well-established fermentation process. The production strain can continuously synthesize SAMe under optimized conditions. Cell isolation and concentration processes enable high-quality cell material for SAMe disulfate tosylate.
Cell Lysis and Ingredient Extraction: Through premium cell lysis and ingredient extraction technologies, Sunjoy efficiently releases SAMe inside cells and increases extraction efficiency. With optimized technologies, Sunjoy lays the foundation for high-assay SAMe disulfate tosylate.
Purification: We combine membrane filtration with multistage purification technologies to remove cell debris, proteins, and other residues. Strict purification processes help ensure reliable assay of SAMe disulfate tosylate and advanced batch consistency.
Salt Formation: We obtain crude SAMe base after extraction and purification. Then SAMe disulfate tosylate is obtained through salt formation. The entire salt-forming process is carried out in a closed-loop, low-temperature environment. Inert gas in the system can successfully isolate SAMe from the air.
Compared with free SAMe, SAMe disulfate tosylate has better storage stability and processing adaptability, meeting the needs of industrial production of nutrition supplements.
Concentration and Drying: Sunjoy strictly controls the process parameters during concentration and drying. We prevent products from the influence of damp and heat, maintaining them in good condition, flowability, and storage stability for subsequent manufacturing and shipping.
| Item | Specifications | ||
| Appearance | White to off-white powder | ||
| Test items | pH(5% Aqueous Solution) | 1.0~2.0 | |
| Water Content(K.F) | ≤3.0% | ||
| S, S-Iomeric Ratio | ≥60.0% | ||
| Lead | ≤3ppm | ||
| Cadmium | ≤1ppm | ||
| Mercury | ≤0.1ppm | ||
| Arsenic | ≤0.5ppm | ||
| Microbiology | Total Aerobic Count | ≤1000 CFU/g | |
| Yeast and Mold Count | ≤100 CFU/g | ||
| Escherichia Coli | Absent in 10g | ||
| Staphylococcus Aureus | Absent in 10g | ||
| Salmonella | Absent in 10g | ||
| Content | Content of Sulfate (SO4) | 23.5%~26.5% (on the anhydrous basis) | |
| SAM ion | 49.5%~54.7% (on the anhydrous basis) | ||
| S-Adenosyl-L-Methionine Disulfate Tosylate | 95.0%~105.0% (on the anhydrous basis) | ||
Related Product
Widely used for prenatal, postnatal, cardiovascular, and nervous system health.
Primarily used to support cognitive health, healthy aging, and cellular energy metabolism.
Generally adopted in sports recovery, protein supplementation, and physical fitness.
| Differences | S-Adenosyl-L-Methionine | L-Methionine |
| Chemical Nature | Bioactive metabolite naturally occurring in the human body | Essential amino acid for the human body |
| Role in the Human Body | Participates in methylation and multiple metabolic pathways | Raw materials used to synthesize SAMe and other components |
| Relationship | Derived from L-Methionine | Precursor of SAMe |
| Main Application | Mood support, liver health, joint health, and healthy aging formulas | Amino acid nutrition, protein supplementation, food fortification, and animal nutrition |
Generally speaking, L-methionine is the raw material of SAMe and SAMe disulfate tosylate, and SAMe is produced from L-methionine. If you are considering manufacturing SAMe disulfate tosylate, L-methionine is your ideal choice of raw material.
SAMe disulfate tosylate is the stable salt form of SAMe, which naturally occurs in the human body. However, SAMe disulfate tosylate can cause mild reactions. In rare cases or at overdoses, SAMe disulfate tosylate may trigger severe reactions.
Gastrointestinal Reactions
If people take SAMe disulfate tosylate on an empty stomach or at high doses, they may feel mild gastrointestinal discomfort. Common reactions include nausea, stomach discomfort, bloating, and mild diarrhea.
Nervous System Reactions
Neurotically sensitive people may suffer from mild anxiety, insomnia, changes in sleep quality, dizziness, or headaches. So, in some formulation applications, it is advised not to use before bedtime.
Emotions and Excitability
Case reports indicate that individuals with bipolar disorder can have an increased risk of transitioning from depression to manic episodes.
Serotonin Syndrome
When taken alongside serotonergic drugs like SSRIs, SNRIs, or tricyclic antidepressants, SAMe disulfate tosylate may cause a dangerous increase in serotonin. Immediate medical attention is necessary.
Allergic Reactions
Some people may be allergic to SAMe. They may experience a skin rash, difficulty breathing, swelling of the tongue or throat, or a racing heart rate.
Precautions
Not enough safety data support long-term use of SAMe disulfate tosylate in pregnant or breastfeeding women. SAMe may decrease the therapeutic efficacy of levodopa and cause dangerous reactions with antidepressants. SAMe may even worsen symptoms of Lesch-Nyhan syndrome.
Keep It Sealed
SAMe disulfate tosylate can absorb moisture. Prolonged exposure to air can damage the powder’s flowability and performance. It is recommended to store products in sealed packaging and prevent exposure to the air.
Store in Cool and Dry Environments
High temperature and moisture can accelerate product degradation, affecting the quality and shelf life of SAMe disulfate tosylate. So, you can store your products in cool, dry, and well-ventilated environments.
Avoid Direct Light
SAMe disulfate tosylate is sensitive to light. Long-term exposure to sunlight or strong light can affect the product’s stability. It is recommended to store your SAMe disulfate tosylate in light-proof environments.
Keep in Original Packaging
Before shipment, SAMe disulfate tosylate is carefully packed in sealed foil bags or fiber drums to protect it from moisture, light, and other environmental factors that may affect its quality. We ensure your product will be safe during shipping. To maintain optimal protection, keep SAMe disulfate tosylate in its original packaging until use.
Quality Documents
To confirm our product quality, we can provide documents such as COAs, specification sheets, and third-party inspection certificates. We also have traceable systems for quality documents. Every batch of SAMe disulfate tosylate needs to undergo quality tests before shipment.
Compliance Documents
Our product quality complies with GMP standards, and our production lines are certified under ISO standards. With compliance statements for the EU, the US, and CN, we ensure our products can enter your target markets smoothly. You need not worry about the destruction of goods caused by non-compliant products.
Shipping and Logistics Documents
Besides inspection and compliance documents, there is other paperwork required for cargo export and import. We are fully engaged in documentation support for you. No matter what document you need, as long as we can provide it, you can contact us for assistance.
Contact Us
If you need premium S-Adenosyl-L-Methionine disulfate tosylate in bulk orders, you can contact Sunjoy. We continuously provide quality-assured products to support your formulation needs and custom requirements.
